Liver microsome · TISSUE · Rattus norvegicus
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Liver microsome
Review this target as Liver microsome.
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This review treats Liver microsome as ChEMBL target CHEMBL2367428. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Liver microsome |
| Target Type | TISSUE |
| Organism | Rattus norvegicus |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as Liver microsome.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3330295 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL427462 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL376316 | 7.81 | IC50 | 15.5 | Preclinical |
| CHEMBL3330296 | 7.48 | IC50 | 33.0 | Preclinical |
| CHEMBL38 | 5.5 | IC50 | 3200.0 | Approved |
| CHEMBL7301 | 5.3 | IC50 | 5000.0 | Clinical |
| CHEMBL2262174 | 5.1 | IC50 | 8000.0 | Preclinical |
| CHEMBL3593745 | 5.0 | IC50 | 10110.0 | Preclinical |
| CHEMBL3593746 | 4.99 | IC50 | 10150.0 | Preclinical |
| CHEMBL3593744 | 4.98 | IC50 | 10540.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 630 | 3 | 4.2 |
| tissue-based format | 154 | 0 | — |
| microsome format | 8 | 0 | — |
| cell-free format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| mitochondrion format | 84 | 0 | — |
| assay format | 19 | 42 | 5.1 |
| tissue-based format | 2 | 4 | 5.1 |