D(1) dopamine receptor · SINGLE PROTEIN · Carassius auratus
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As of 2026-09-14Protein identity stays anchored to UniProt P35406. Use UniProt P35406 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P35406 as the stable identity anchor, then attach disease evidence before program review.
D(1) dopamine receptor
Review this target as D(1) dopamine receptor, mapped to UniProt P35406. Sequence length is 363 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats D(1) dopamine receptor as ChEMBL target CHEMBL2368, mapped to UniProt P35406. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | D(1) dopamine receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Carassius auratus |
| UniProt | P35406 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | D(1) dopamine receptor |
| UniProt Accession | P35406 |
| Component Type | Protein |
| Sequence Length | 363 aa |
D(1) dopamine receptor
Review this target as D(1) dopamine receptor, mapped to UniProt P35406. Sequence length is 363 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL62 | 8.89 | Ki | 1.3 | Preclinical |
| CHEMBL291143 | 8.09 | EC50 | 8.2 | Preclinical |
| CHEMBL41132 | 7.96 | EC50 | 11.0 | Preclinical |
| CHEMBL2114444 | 7.66 | EC50 | 22.0 | Preclinical |
| CHEMBL2114441 | 7.62 | EC50 | 24.0 | Preclinical |
| CHEMBL28338 | 7.62 | EC50 | 24.0 | Preclinical |
| CHEMBL291100 | 7.55 | EC50 | 28.0 | Preclinical |
| CHEMBL40667 | 7.55 | EC50 | 28.0 | Preclinical |
| CHEMBL446350 | 7.54 | EC50 | 29.0 | Preclinical |
| CHEMBL2115377 | 7.51 | EC50 | 31.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 9 | 7.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |
| tissue-based format | 1 | 35 | 7.0 |