Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q921V5. Use UniProt Q921V5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q921V5 as the stable identity anchor, then attach disease evidence before program review.
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
Review this target as Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, mapped to UniProt Q921V5. Sequence length is 442 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase as ChEMBL target CHEMBL2375203, mapped to UniProt Q921V5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q921V5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
| UniProt Accession | Q921V5 |
| Component Type | Protein |
| Sequence Length | 442 aa |
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
Review this target as Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, mapped to UniProt Q921V5. Sequence length is 442 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3893594 | 9.24 | IC50 | 0.58 | Preclinical |
| CHEMBL4457459 | 9.14 | IC50 | 0.73 | Preclinical |
| CHEMBL4847167 | 8.68 | IC50 | 2.1 | Preclinical |
| CHEMBL5411481 | 8.64 | IC50 | 2.3 | Preclinical |
| CHEMBL4455357 | 8.62 | IC50 | 2.4 | Preclinical |
| CHEMBL3943482 | 8.47 | IC50 | 3.4 | Preclinical |
| CHEMBL2376325 | 8.4 | IC50 | 3.981 | Preclinical |
| CHEMBL5416977 | 8.32 | IC50 | 4.8 | Preclinical |
| CHEMBL2376303 | 8.3 | IC50 | 5.012 | Preclinical |
| CHEMBL4872250 | 8.3 | IC50 | 5.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 14 | 8.0 |
| cell-based format | 2 | 10 | 7.7 |
| cell membrane format | 1 | 47 | 7.3 |
| microsome format | 1 | 1 | 7.1 |