Adenylate kinase 2, mitochondrial · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P29410. Use UniProt P29410 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P29410 as the stable identity anchor, then attach disease evidence before program review.
Adenylate kinase 2, mitochondrial
Review this target as Adenylate kinase 2, mitochondrial, mapped to UniProt P29410. Sequence length is 239 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Adenylate kinase 2, mitochondrial as ChEMBL target CHEMBL2376, mapped to UniProt P29410. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Adenylate kinase 2, mitochondrial |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P29410 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Adenylate kinase 2, mitochondrial |
| UniProt Accession | P29410 |
| Component Type | Protein |
| Sequence Length | 239 aa |
Adenylate kinase 2, mitochondrial
Review this target as Adenylate kinase 2, mitochondrial, mapped to UniProt P29410. Sequence length is 239 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL604399 | 7.22 | Ki | 60.0 | Preclinical |
| CHEMBL437508 | 6.55 | Ki | 280.0 | Preclinical |
| CHEMBL605639 | 5.82 | Ki | 1500.0 | Preclinical |
| CHEMBL606017 | 5.19 | Ki | 6400.0 | Preclinical |
| CHEMBL605430 | 4.28 | Ki | 52000.0 | Preclinical |
| CHEMBL3251359 | 4.26 | Ki | 55000.0 | Preclinical |
| CHEMBL2364580 | 4.12 | Ki | 75000.0 | Preclinical |
| CHEMBL3251358 | 4.1 | Ki | 80000.0 | Preclinical |
| CHEMBL3251360 | 4.1 | Ki | 80000.0 | Preclinical |
| CHEMBL752 | 4.1 | Ki | 80000.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 32 | 40 | 5.5 |
| assay format | 3 | 8 | 4.1 |
| tissue-based format | 1 | 1 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 0 | — |