M-phase inducer phosphatase 3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P30307. Use UniProt P30307 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P30307 as the stable identity anchor, then attach disease evidence before program review.
M-phase inducer phosphatase 3
Review this target as M-phase inducer phosphatase 3, mapped to UniProt P30307. Sequence length is 473 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats M-phase inducer phosphatase 3 as ChEMBL target CHEMBL2378, mapped to UniProt P30307. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | M-phase inducer phosphatase 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P30307 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | M-phase inducer phosphatase 3 |
| UniProt Accession | P30307 |
| Component Type | Protein |
| Sequence Length | 473 aa |
M-phase inducer phosphatase 3
Review this target as M-phase inducer phosphatase 3, mapped to UniProt P30307. Sequence length is 473 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5271462 | 7.64 | IC50 | 23.0 | Preclinical |
| CHEMBL5288122 | 7.64 | IC50 | 23.0 | Preclinical |
| CHEMBL429095 | 7.25 | IC50 | 56.9 | Preclinical |
| CHEMBL5423941 | 7.22 | IC50 | 60.0 | Preclinical |
| CHEMBL5560222 | 7.22 | IC50 | 60.0 | Preclinical |
| CHEMBL337173 | 7.05 | Ki | 89.0 | Preclinical |
| CHEMBL4521092 | 7.05 | IC50 | 90.0 | Preclinical |
| CHEMBL4093222 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL199359 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL382593 | 6.89 | IC50 | 130.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 32 | 77 | 5.3 |
| cell-based format | 16 | 4 | 5.9 |
| assay format | 8 | 30 | 5.4 |