Protein mono-ADP-ribosyltransferase PARP11 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9NR21. Use UniProt Q9NR21 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9NR21 as the stable identity anchor, then attach disease evidence before program review.
Protein mono-ADP-ribosyltransferase PARP11
Review this target as Protein mono-ADP-ribosyltransferase PARP11, mapped to UniProt Q9NR21. Sequence length is 338 aa.
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This review treats Protein mono-ADP-ribosyltransferase PARP11 as ChEMBL target CHEMBL2380189, mapped to UniProt Q9NR21. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Protein mono-ADP-ribosyltransferase PARP11 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9NR21 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Protein mono-ADP-ribosyltransferase PARP11 |
| UniProt Accession | Q9NR21 |
| Component Type | Protein |
| Sequence Length | 338 aa |
Protein mono-ADP-ribosyltransferase PARP11
Review this target as Protein mono-ADP-ribosyltransferase PARP11, mapped to UniProt Q9NR21. Sequence length is 338 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5191676 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL5199558 | 7.17 | IC50 | 67.0 | Preclinical |
| CHEMBL5207717 | 7.0 | IC50 | 99.0 | Preclinical |
| CHEMBL3137320 | 6.85 | IC50 | 140.0 | Approved |
| CHEMBL5187963 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL5404785 | 6.62 | IC50 | 240.0 | Preclinical |
| CHEMBL5431108 | 6.33 | IC50 | 467.74 | Preclinical |
| CHEMBL5186007 | 6.26 | IC50 | 550.0 | Preclinical |
| CHEMBL4580007 | 5.93 | IC50 | 1174.9 | Preclinical |
| CHEMBL125200 | 5.68 | IC50 | 2100.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 14 | 7 | 6.2 |
| cell-based format | 8 | 5 | 6.6 |
| assay format | 4 | 29 | 5.1 |