Bone morphogenetic protein 4 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P21275. Use UniProt P21275 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P21275 as the stable identity anchor, then attach disease evidence before program review.
Bone morphogenetic protein 4
Review this target as Bone morphogenetic protein 4, mapped to UniProt P21275. Sequence length is 408 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Bone morphogenetic protein 4 as ChEMBL target CHEMBL2384894, mapped to UniProt P21275. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Bone morphogenetic protein 4 is the right protein anchor across sources, using UniProt P21275 as the stable mapping.
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| Preferred Name | Bone morphogenetic protein 4 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P21275 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Bone morphogenetic protein 4 |
| UniProt Accession | P21275 |
| Component Type | Protein |
| Sequence Length | 408 aa |
Bone morphogenetic protein 4
Review this target as Bone morphogenetic protein 4, mapped to UniProt P21275. Sequence length is 408 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2385596 | 7.6 | IC50 | 25.2 | Preclinical |
| CHEMBL2385600 | 7.03 | IC50 | 94.1 | Preclinical |
| CHEMBL2385591 | 6.93 | IC50 | 117.0 | Preclinical |
| CHEMBL2385579 | 6.85 | IC50 | 141.0 | Preclinical |
| CHEMBL502351 | 6.82 | IC50 | 152.0 | Preclinical |
| CHEMBL2385588 | 6.61 | IC50 | 246.0 | Preclinical |
| CHEMBL2385585 | 6.38 | IC50 | 418.0 | Preclinical |
| CHEMBL2385581 | 6.28 | IC50 | 529.0 | Preclinical |
| CHEMBL2385595 | 6.28 | IC50 | 523.0 | Preclinical |
| CHEMBL2385592 | 5.58 | IC50 | 2636.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 12 | 6.4 |