Adenosylhomocysteinase · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P50247. Use UniProt P50247 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P50247 as the stable identity anchor, then attach disease evidence before program review.
Adenosylhomocysteinase
Review this target as Adenosylhomocysteinase, mapped to UniProt P50247. Sequence length is 432 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Adenosylhomocysteinase as ChEMBL target CHEMBL2389, mapped to UniProt P50247. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Adenosylhomocysteinase |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P50247 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Adenosylhomocysteinase |
| UniProt Accession | P50247 |
| Component Type | Protein |
| Sequence Length | 432 aa |
Adenosylhomocysteinase
Review this target as Adenosylhomocysteinase, mapped to UniProt P50247. Sequence length is 432 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL8771 | 8.52 | Ki | 3.0 | Preclinical |
| CHEMBL8275 | 7.96 | Ki | 11.1 | Preclinical |
| CHEMBL8771 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL327105 | 7.07 | Ki | 86.0 | Preclinical |
| CHEMBL299135 | 6.82 | Ki | 150.0 | Preclinical |
| CHEMBL45769 | 6.26 | Ki | 550.0 | Preclinical |
| CHEMBL297437 | 5.98 | Ki | 1040.0 | Preclinical |
| CHEMBL609353 | 5.0 | Ki | 10000.0 | Preclinical |
| CHEMBL1090 | 4.52 | Ki | 30000.0 | Approved |
| CHEMBL113259 | 4.25 | Ki | 55700.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 8 | 4 | 5.4 |
| cell-based format | 4 | 11 | 6.0 |
| single protein format | 1 | 3 | 6.0 |