G protein-coupled receptor GPR35 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt Q33BM1. Use UniProt Q33BM1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q33BM1 as the stable identity anchor, then attach disease evidence before program review.
G protein-coupled receptor GPR35
Review this target as G protein-coupled receptor GPR35, mapped to UniProt Q33BM1. Sequence length is 306 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats G protein-coupled receptor GPR35 as ChEMBL target CHEMBL2390812, mapped to UniProt Q33BM1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | G protein-coupled receptor GPR35 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q33BM1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | G protein-coupled receptor GPR35 |
| UniProt Accession | Q33BM1 |
| Component Type | Protein |
| Sequence Length | 306 aa |
G protein-coupled receptor GPR35
Review this target as G protein-coupled receptor GPR35, mapped to UniProt Q33BM1. Sequence length is 306 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL28079 | 7.21 | EC50 | 61.1 | Clinical |
| CHEMBL1201198 | 7.02 | EC50 | 95.0 | Approved |
| CHEMBL74 | 6.01 | EC50 | 986.0 | Approved |
| CHEMBL2392183 | 6.0 | EC50 | 991.0 | Preclinical |
| CHEMBL2392176 | 5.96 | EC50 | 1100.0 | Preclinical |
| CHEMBL2392148 | 5.92 | EC50 | 1200.0 | Preclinical |
| CHEMBL2392177 | 5.89 | EC50 | 1300.0 | Preclinical |
| CHEMBL2392175 | 5.87 | EC50 | 1360.0 | Preclinical |
| CHEMBL2392174 | 5.85 | EC50 | 1400.0 | Preclinical |
| CHEMBL2392182 | 5.81 | EC50 | 1540.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 28 | 5.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 1 | 7.0 |