5'-AMP-activated protein kinase subunit gamma-1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P54619. Use UniProt P54619 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P54619 as the stable identity anchor, then attach disease evidence before program review.
5'-AMP-activated protein kinase subunit gamma-1
Review this target as 5'-AMP-activated protein kinase subunit gamma-1, mapped to UniProt P54619. Sequence length is 331 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 5'-AMP-activated protein kinase subunit gamma-1 as ChEMBL target CHEMBL2393, mapped to UniProt P54619. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | 5'-AMP-activated protein kinase subunit gamma-1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P54619 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 5'-AMP-activated protein kinase subunit gamma-1 |
| UniProt Accession | P54619 |
| Component Type | Protein |
| Sequence Length | 331 aa |
5'-AMP-activated protein kinase subunit gamma-1
Review this target as 5'-AMP-activated protein kinase subunit gamma-1, mapped to UniProt P54619. Sequence length is 331 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3128043 | 8.22 | Kd | 6.0 | Preclinical |
| CHEMBL5653589 | 7.73 | Kd | 18.49 | Preclinical |
| CHEMBL495727 | 7.47 | Kd | 34.0 | Clinical |
| CHEMBL402548 | 7.1 | Kd | 79.0 | Clinical |
| CHEMBL3688339 | 6.82 | Kd | 150.0 | Preclinical |
| CHEMBL281948 | 6.45 | Kd | 352.0 | Preclinical |
| CHEMBL3544932 | 6.45 | Kd | 355.0 | Preclinical |
| CHEMBL575448 | 6.39 | Kd | 409.0 | Clinical |
| CHEMBL2041933 | 6.23 | Kd | 587.0 | Preclinical |
| CHEMBL3545137 | 6.11 | Kd | 784.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 2 | 6.7 |
| subcellular format | 2 | 25 | 6.1 |
| cell-based format | 1 | 0 | — |