Apelin receptor · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q9JHG3. Use UniProt Q9JHG3 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9JHG3 as the stable identity anchor, then attach disease evidence before program review.
Apelin receptor
Review this target as Apelin receptor, mapped to UniProt Q9JHG3. Sequence length is 377 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Apelin receptor as ChEMBL target CHEMBL2398, mapped to UniProt Q9JHG3. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Apelin receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q9JHG3 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Apelin receptor |
| UniProt Accession | Q9JHG3 |
| Component Type | Protein |
| Sequence Length | 377 aa |
Apelin receptor
Review this target as Apelin receptor, mapped to UniProt Q9JHG3. Sequence length is 377 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4850818 | 11.0 | EC50 | 0.01 | Preclinical |
| CHEMBL4851100 | 10.7 | EC50 | 0.02 | Preclinical |
| CHEMBL4872345 | 10.7 | EC50 | 0.02 | Preclinical |
| CHEMBL4874447 | 10.7 | EC50 | 0.02 | Preclinical |
| CHEMBL4878056 | 10.7 | EC50 | 0.02 | Preclinical |
| CHEMBL4861895 | 10.62 | EC50 | 0.024 | Preclinical |
| CHEMBL4873876 | 10.62 | EC50 | 0.024 | Preclinical |
| CHEMBL3234446 | 10.6 | IC50 | 0.025 | Preclinical |
| CHEMBL4855918 | 10.52 | EC50 | 0.03 | Preclinical |
| CHEMBL4854412 | 10.46 | EC50 | 0.035 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 8 | 64 | 8.4 |
| assay format | 1 | 21 | 9.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 7 | 17 | 9.5 |
| cell membrane format | 2 | 37 | 9.1 |