Chymotrypsin-like elastase family member 2A · SINGLE PROTEIN · Sus scrofa
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As of 2026-09-14Protein identity stays anchored to UniProt P08419. Use UniProt P08419 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P08419 as the stable identity anchor, then attach disease evidence before program review.
Chymotrypsin-like elastase family member 2A
Review this target as Chymotrypsin-like elastase family member 2A, mapped to UniProt P08419. Sequence length is 269 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Chymotrypsin-like elastase family member 2A as ChEMBL target CHEMBL2407, mapped to UniProt P08419. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Chymotrypsin-like elastase family member 2A |
| Target Type | SINGLE PROTEIN |
| Organism | Sus scrofa |
| UniProt | P08419 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Chymotrypsin-like elastase family member 2A |
| UniProt Accession | P08419 |
| Component Type | Protein |
| Sequence Length | 269 aa |
Chymotrypsin-like elastase family member 2A
Review this target as Chymotrypsin-like elastase family member 2A, mapped to UniProt P08419. Sequence length is 269 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL290577 | 9.44 | Ki | 0.365 | Preclinical |
| CHEMBL108294 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL288176 | 8.66 | Ki | 2.2 | Preclinical |
| CHEMBL3349045 | 8.51 | Ki | 3.08 | Preclinical |
| CHEMBL291026 | 8.34 | Ki | 4.56 | Preclinical |
| CHEMBL285285 | 8.14 | Ki | 7.25 | Preclinical |
| CHEMBL418050 | 8.09 | Ki | 8.08 | Preclinical |
| CHEMBL79463 | 7.89 | Ki | 13.0 | Preclinical |
| CHEMBL134821 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL319723 | 7.82 | Ki | 15.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 99 | 124 | 6.1 |