Cytochrome P450 2C18 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P33260. Use UniProt P33260 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P33260 as the stable identity anchor, then attach disease evidence before program review.
Cytochrome P450 2C18
Review this target as Cytochrome P450 2C18, mapped to UniProt P33260. Sequence length is 490 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cytochrome P450 2C18 as ChEMBL target CHEMBL2408, mapped to UniProt P33260. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Cytochrome P450 2C18 is the right protein anchor across sources, using UniProt P33260 as the stable mapping.
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| Preferred Name | Cytochrome P450 2C18 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P33260 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cytochrome P450 2C18 |
| UniProt Accession | P33260 |
| Component Type | Protein |
| Sequence Length | 490 aa |
Cytochrome P450 2C18
Review this target as Cytochrome P450 2C18, mapped to UniProt P33260. Sequence length is 490 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL121323 | 5.52 | IC50 | 3000.0 | Preclinical |
| CHEMBL121503 | 5.52 | IC50 | 3000.0 | Preclinical |
| CHEMBL121420 | 5.4 | IC50 | 4000.0 | Preclinical |
| CHEMBL120426 | 5.3 | IC50 | 5000.0 | Preclinical |
| CHEMBL331485 | 5.22 | IC50 | 6000.0 | Preclinical |
| CHEMBL120797 | 5.16 | IC50 | 7000.0 | Preclinical |
| CHEMBL330871 | 5.16 | IC50 | 7000.0 | Preclinical |
| CHEMBL120183 | 5.1 | IC50 | 8000.0 | Preclinical |
| CHEMBL121522 | 5.1 | IC50 | 8000.0 | Preclinical |
| CHEMBL121048 | 5.05 | IC50 | 9000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 9 | 0 | — |
| assay format | 4 | 24 | 5.0 |
| cell membrane format | 1 | 0 | — |
| cell-based format | 1 | 0 | — |