Transcriptional regulator MvfR · SINGLE PROTEIN · Pseudomonas aeruginosa PA14
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As of 2026-09-14Protein identity stays anchored to UniProt A0A072ZLE6. Use UniProt A0A072ZLE6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt A0A072ZLE6 as the stable identity anchor, then attach disease evidence before program review.
DNA-binding transcriptional regulator
Review this target as Transcriptional regulator MvfR, mapped to UniProt A0A072ZLE6. ChEMBL maps the protein component as DNA-binding transcriptional regulator. Sequence length is 332 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Transcriptional regulator MvfR as ChEMBL target CHEMBL2424500, mapped to UniProt A0A072ZLE6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Transcriptional regulator MvfR |
| Target Type | SINGLE PROTEIN |
| Organism | Pseudomonas aeruginosa PA14 |
| UniProt | A0A072ZLE6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | DNA-binding transcriptional regulator |
| UniProt Accession | A0A072ZLE6 |
| Component Type | Protein |
| Sequence Length | 332 aa |
DNA-binding transcriptional regulator
Review this target as Transcriptional regulator MvfR, mapped to UniProt A0A072ZLE6. ChEMBL maps the protein component as DNA-binding transcriptional regulator. Sequence length is 332 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5613568 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL5614116 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL5613188 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL5614294 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL5613166 | 8.05 | IC50 | 9.0 | Preclinical |
| CHEMBL5613313 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL5090908 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL5612748 | 7.77 | IC50 | 17.0 | Preclinical |
| CHEMBL5612433 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL5613132 | 7.72 | IC50 | 19.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 45 | 57 | 6.5 |
| assay format | 27 | 50 | 5.7 |