Mitogen-activated protein kinase kinase kinase 11 · SINGLE PROTEIN · Mus musculus
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q80XI6. Use UniProt Q80XI6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q80XI6 as the stable identity anchor, then attach disease evidence before program review.
Mitogen-activated protein kinase kinase kinase 11
Review this target as Mitogen-activated protein kinase kinase kinase 11, mapped to UniProt Q80XI6. Sequence length is 850 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Mitogen-activated protein kinase kinase kinase 11 as ChEMBL target CHEMBL2434817, mapped to UniProt Q80XI6. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Mitogen-activated protein kinase kinase kinase 11 is the right protein anchor across sources, using UniProt Q80XI6 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Mitogen-activated protein kinase kinase kinase 11 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q80XI6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Mitogen-activated protein kinase kinase kinase 11 |
| UniProt Accession | Q80XI6 |
| Component Type | Protein |
| Sequence Length | 850 aa |
Mitogen-activated protein kinase kinase kinase 11
Review this target as Mitogen-activated protein kinase kinase kinase 11, mapped to UniProt Q80XI6. Sequence length is 850 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2436982 | 6.92 | IC50 | 120.0 | Preclinical |
| CHEMBL2436981 | 6.37 | IC50 | 430.0 | Preclinical |
| CHEMBL2436978 | 6.34 | IC50 | 460.0 | Preclinical |
| CHEMBL2436983 | 6.29 | IC50 | 510.0 | Preclinical |
| CHEMBL2436976 | 6.0 | IC50 | 990.0 | Preclinical |
| CHEMBL2436980 | 5.57 | IC50 | 2700.0 | Preclinical |
| CHEMBL2436979 | 4.63 | IC50 | 23600.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 7 | 6.0 |
| subcellular format | 1 | 0 | — |