Peroxisome proliferator-activated receptor gamma · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P37238. Use UniProt P37238 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P37238 as the stable identity anchor, then attach disease evidence before program review.
Peroxisome proliferator-activated receptor gamma
Review this target as Peroxisome proliferator-activated receptor gamma, mapped to UniProt P37238. Sequence length is 505 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Peroxisome proliferator-activated receptor gamma as ChEMBL target CHEMBL2459, mapped to UniProt P37238. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Peroxisome proliferator-activated receptor gamma |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P37238 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Peroxisome proliferator-activated receptor gamma |
| UniProt Accession | P37238 |
| Component Type | Protein |
| Sequence Length | 505 aa |
Peroxisome proliferator-activated receptor gamma
Review this target as Peroxisome proliferator-activated receptor gamma, mapped to UniProt P37238. Sequence length is 505 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5207130 | 9.85 | IC50 | 0.14 | Preclinical |
| CHEMBL107367 | 9.46 | EC50 | 0.35 | Clinical |
| CHEMBL106666 | 8.92 | EC50 | 1.2 | Preclinical |
| CHEMBL602468 | 8.7 | EC50 | 2.0 | Preclinical |
| CHEMBL3115237 | 8.52 | EC50 | 3.0 | Preclinical |
| CHEMBL5288454 | 8.39 | EC50 | 4.1 | Preclinical |
| CHEMBL423026 | 8.33 | EC50 | 4.677 | Preclinical |
| CHEMBL5267263 | 8.06 | IC50 | 8.7 | Preclinical |
| CHEMBL3115238 | 8.05 | EC50 | 9.0 | Preclinical |
| CHEMBL278994 | 8.0 | EC50 | 10.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 175 | 62 | 6.4 |
| single protein format | 16 | 12 | 6.2 |
| organism-based format | 7 | 0 | — |
| assay format | 4 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 25 | 137 | 6.4 |
| assay format | 9 | 26 | 6.5 |
| organism-based format | 6 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 14 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 0 | — |