Acetylcholine receptor subunit epsilon · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q04844. Use UniProt Q04844 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q04844 as the stable identity anchor, then attach disease evidence before program review.
Acetylcholine receptor subunit epsilon
Review this target as Acetylcholine receptor subunit epsilon, mapped to UniProt Q04844. Sequence length is 493 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Acetylcholine receptor subunit epsilon as ChEMBL target CHEMBL2484, mapped to UniProt Q04844. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Acetylcholine receptor subunit epsilon |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q04844 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Acetylcholine receptor subunit epsilon |
| UniProt Accession | Q04844 |
| Component Type | Protein |
| Sequence Length | 493 aa |
Acetylcholine receptor subunit epsilon
Review this target as Acetylcholine receptor subunit epsilon, mapped to UniProt Q04844. Sequence length is 493 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5179810 | 8.64 | IC50 | 2.291 | Preclinical |
| CHEMBL4473371 | 8.51 | Ki | 3.07 | Preclinical |
| CHEMBL4435544 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL5204683 | 7.92 | IC50 | 12.02 | Preclinical |
| CHEMBL4471876 | 7.57 | IC50 | 27.0 | Preclinical |
| CHEMBL502 | 7.49 | IC50 | 32.36 | Approved |
| CHEMBL5181578 | 7.49 | IC50 | 32.36 | Preclinical |
| CHEMBL5176418 | 7.44 | IC50 | 36.31 | Preclinical |
| CHEMBL95 | 7.36 | IC50 | 44.0 | Approved |
| CHEMBL5173121 | 7.36 | IC50 | 43.65 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 17 | 29 | 7.2 |
| assay format | 1 | 0 | — |