Prostaglandin E2 receptor EP4 subtype · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P32240. Use UniProt P32240 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P32240 as the stable identity anchor, then attach disease evidence before program review.
Prostaglandin E2 receptor EP4 subtype
Review this target as Prostaglandin E2 receptor EP4 subtype, mapped to UniProt P32240. Sequence length is 513 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Prostaglandin E2 receptor EP4 subtype as ChEMBL target CHEMBL2489, mapped to UniProt P32240. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Prostaglandin E2 receptor EP4 subtype |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P32240 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Prostaglandin E2 receptor EP4 subtype |
| UniProt Accession | P32240 |
| Component Type | Protein |
| Sequence Length | 513 aa |
Prostaglandin E2 receptor EP4 subtype
Review this target as Prostaglandin E2 receptor EP4 subtype, mapped to UniProt P32240. Sequence length is 513 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1957437 | 10.92 | Ki | 0.012 | Preclinical |
| CHEMBL2036314 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL2036322 | 9.92 | Ki | 0.12 | Preclinical |
| CHEMBL2036323 | 9.92 | Ki | 0.12 | Preclinical |
| CHEMBL2037291 | 9.82 | Ki | 0.15 | Preclinical |
| CHEMBL2037289 | 9.8 | Ki | 0.16 | Preclinical |
| CHEMBL2036324 | 9.72 | Ki | 0.19 | Preclinical |
| CHEMBL2036312 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL2037292 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL2036326 | 9.68 | Ki | 0.21 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 15 | 174 | 7.8 |
| single protein format | 3 | 5 | 6.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 7 | 54 | 7.5 |
| single protein format | 1 | 2 | 7.0 |