Serine/threonine-protein phosphatase 2A activator · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q15257. Use UniProt Q15257 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q15257 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein phosphatase 2A activator
Review this target as Serine/threonine-protein phosphatase 2A activator, mapped to UniProt Q15257. Sequence length is 358 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein phosphatase 2A activator as ChEMBL target CHEMBL2505, mapped to UniProt Q15257. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Serine/threonine-protein phosphatase 2A activator is the right protein anchor across sources, using UniProt Q15257 as the stable mapping.
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| Preferred Name | Serine/threonine-protein phosphatase 2A activator |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q15257 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein phosphatase 2A activator |
| UniProt Accession | Q15257 |
| Component Type | Protein |
| Sequence Length | 358 aa |
Serine/threonine-protein phosphatase 2A activator
Review this target as Serine/threonine-protein phosphatase 2A activator, mapped to UniProt Q15257. Sequence length is 358 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL40248 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL295239 | 5.4 | IC50 | 4000.0 | Preclinical |
| CHEMBL505512 | 5.03 | IC50 | 9400.0 | Preclinical |
| CHEMBL602231 | 4.64 | IC50 | 23100.0 | Preclinical |
| CHEMBL40247 | 4.54 | IC50 | 29000.0 | Preclinical |
| CHEMBL599646 | 4.3 | IC50 | 49700.0 | Preclinical |
| CHEMBL295238 | 4.0 | IC50 | 100000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 15 | 7 | 5.0 |
| assay format | 1 | 2 | 4.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |