Beta-galactosidase · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P16278. Use UniProt P16278 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P16278 as the stable identity anchor, then attach disease evidence before program review.
Beta-galactosidase
Review this target as Beta-galactosidase, mapped to UniProt P16278. Sequence length is 677 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-galactosidase as ChEMBL target CHEMBL2522, mapped to UniProt P16278. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
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Start here when your first question is whether Beta-galactosidase is the right protein anchor across sources, using UniProt P16278 as the stable mapping.
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| Preferred Name | Beta-galactosidase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P16278 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-galactosidase |
| UniProt Accession | P16278 |
| Component Type | Protein |
| Sequence Length | 677 aa |
Beta-galactosidase
Review this target as Beta-galactosidase, mapped to UniProt P16278. Sequence length is 677 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4288931 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL4085739 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL4284436 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL1922581 | 6.9 | IC50 | 125.0 | Preclinical |
| CHEMBL3771185 | 6.68 | IC50 | 210.0 | Preclinical |
| CHEMBL1818433 | 6.62 | IC50 | 240.0 | Preclinical |
| CHEMBL4281031 | 6.6 | IC50 | 250.0 | Preclinical |
| CHEMBL4069909 | 6.54 | Ki | 290.0 | Preclinical |
| CHEMBL1922581 | 6.52 | Ki | 300.0 | Preclinical |
| CHEMBL205982 | 6.52 | Ki | 300.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 86 | 37 | 5.4 |
| assay format | 35 | 18 | 5.5 |
| tissue-based format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 0 | — |