Disintegrin and metalloproteinase domain-containing protein 17 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q9Z1K9. Use UniProt Q9Z1K9 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9Z1K9 as the stable identity anchor, then attach disease evidence before program review.
Disintegrin and metalloproteinase domain-containing protein 17
Review this target as Disintegrin and metalloproteinase domain-containing protein 17, mapped to UniProt Q9Z1K9. Sequence length is 827 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Disintegrin and metalloproteinase domain-containing protein 17 as ChEMBL target CHEMBL2523, mapped to UniProt Q9Z1K9. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Disintegrin and metalloproteinase domain-containing protein 17 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q9Z1K9 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Disintegrin and metalloproteinase domain-containing protein 17 |
| UniProt Accession | Q9Z1K9 |
| Component Type | Protein |
| Sequence Length | 827 aa |
Disintegrin and metalloproteinase domain-containing protein 17
Review this target as Disintegrin and metalloproteinase domain-containing protein 17, mapped to UniProt Q9Z1K9. Sequence length is 827 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL435102 | 8.77 | IC50 | 1.7 | Preclinical |
| CHEMBL363126 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL185168 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL183995 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL365283 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL365658 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL364643 | 7.64 | IC50 | 23.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 4 | 0 | — |
| cell-free format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 7 | 8.0 |