P2X purinoceptor 2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9UBL9. Use UniProt Q9UBL9 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UBL9 as the stable identity anchor, then attach disease evidence before program review.
P2X purinoceptor 2
Review this target as P2X purinoceptor 2, mapped to UniProt Q9UBL9. Sequence length is 471 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats P2X purinoceptor 2 as ChEMBL target CHEMBL2531, mapped to UniProt Q9UBL9. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | P2X purinoceptor 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UBL9 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | P2X purinoceptor 2 |
| UniProt Accession | Q9UBL9 |
| Component Type | Protein |
| Sequence Length | 471 aa |
P2X purinoceptor 2
Review this target as P2X purinoceptor 2, mapped to UniProt Q9UBL9. Sequence length is 471 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5202979 | 8.43 | IC50 | 3.715 | Preclinical |
| CHEMBL5913570 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL5975386 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL5764480 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL5815661 | 7.77 | IC50 | 17.0 | Preclinical |
| CHEMBL5999082 | 7.72 | IC50 | 19.0 | Preclinical |
| CHEMBL6008060 | 7.66 | IC50 | 22.0 | Preclinical |
| CHEMBL5886721 | 7.64 | IC50 | 23.0 | Preclinical |
| CHEMBL5853218 | 7.57 | IC50 | 27.0 | Preclinical |
| CHEMBL5908564 | 7.57 | IC50 | 27.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 32 | 456 | 6.3 |
| single protein format | 12 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 8 | 5 | 5.3 |
| cell-based format | 3 | 0 | — |