Solute carrier family 2, facilitated glucose transporter member 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P11166. Use UniProt P11166 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P11166 as the stable identity anchor, then attach disease evidence before program review.
Solute carrier family 2, facilitated glucose transporter member 1
Review this target as Solute carrier family 2, facilitated glucose transporter member 1, mapped to UniProt P11166. Sequence length is 492 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Solute carrier family 2, facilitated glucose transporter member 1 as ChEMBL target CHEMBL2535, mapped to UniProt P11166. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Solute carrier family 2, facilitated glucose transporter member 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P11166 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Solute carrier family 2, facilitated glucose transporter member 1 |
| UniProt Accession | P11166 |
| Component Type | Protein |
| Sequence Length | 492 aa |
Solute carrier family 2, facilitated glucose transporter member 1
Review this target as Solute carrier family 2, facilitated glucose transporter member 1, mapped to UniProt P11166. Sequence length is 492 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5661873 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL3780239 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5661842 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5661847 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5661848 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4448899 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5661896 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5661910 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5661838 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL5661843 | 8.52 | IC50 | 3.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 107 | 299 | 6.0 |
| single protein format | 7 | 6 | 6.2 |
| assay format | 6 | 12 | 6.5 |
| tissue-based format | 5 | 0 | — |
| cell membrane format | 4 | 8 | 5.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 23 | 16 | 4.8 |
| mitochondrion format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 436 | 5.4 |
| cell-based format | 1 | 3 | 6.0 |