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Target Snapshot

CHEMBL2560 Target Snapshot

Protein kinase C delta type · SINGLE PROTEIN · Mus musculus

42Compounds
75Assays
0Approved Drugs
115.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt P28867. Use UniProt P28867 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P28867 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Protein kinase C delta type as ChEMBL target CHEMBL2560, mapped to UniProt P28867. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Protein kinase C delta type
SINGLE PROTEIN · Mus musculus
As of 2026-09-13
ChEMBL target ID
CHEMBL2560
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
P28867
Protein kinase C delta type
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Protein kinase C delta type is the right protein anchor across sources, using UniProt P28867 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelProtein kinase C delta type
UniProt AccessionP28867
Component TypeProtein
Sequence Length674 aa

Protein kinase C delta type

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Protein kinase C delta type, mapped to UniProt P28867. Sequence length is 674 aa.

Mapped IDP28867
Review nameProtein kinase C delta type
OrganismMus musculus
Assay Mix

Activity Type Distribution

KI98.0
KD17.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL285801 10.0 Ki 0.1 Preclinical
CHEMBL132720 9.96 Ki 0.11 Preclinical
CHEMBL46094 9.89 Ki 0.13 Preclinical
CHEMBL334853 9.85 Ki 0.14 Preclinical
CHEMBL27768 9.64 Kd 0.23 Preclinical
CHEMBL337834 9.48 Ki 0.33 Preclinical
CHEMBL27768 9.48 Ki 0.33 Preclinical
CHEMBL116437 9.46 Ki 0.351 Preclinical
CHEMBL133853 9.32 Ki 0.48 Preclinical
CHEMBL3262941 9.3 Kd 0.5 Preclinical
Distribution

pChEMBL Value Distribution

3
5.0
9
5.5
9
6.0
4
6.5
11
7.0
18
7.5
7
8.0
19
8.5
19
9.0
5
9.5
pChEMBL
Assay Landscape

Assay Landscape

75
Total Assays
42
Tested Compounds
2
Assay Types
Binding — 71 assays, 42 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 64 17 8.1
assay format 6 23 7.5
subcellular format 1 2 9.1
Functional — 4 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 4 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine