Protein kinase C alpha type · SINGLE PROTEIN · Mus musculus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P20444. Use UniProt P20444 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P20444 as the stable identity anchor, then attach disease evidence before program review.
Protein kinase C alpha type
Review this target as Protein kinase C alpha type, mapped to UniProt P20444. Sequence length is 672 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Protein kinase C alpha type as ChEMBL target CHEMBL2567, mapped to UniProt P20444. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Protein kinase C alpha type is the right protein anchor across sources, using UniProt P20444 as the stable mapping.
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| Preferred Name | Protein kinase C alpha type |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P20444 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Protein kinase C alpha type |
| UniProt Accession | P20444 |
| Component Type | Protein |
| Sequence Length | 672 aa |
Protein kinase C alpha type
Review this target as Protein kinase C alpha type, mapped to UniProt P20444. Sequence length is 672 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL527875 | 8.68 | Ki | 2.07 | Preclinical |
| CHEMBL516638 | 8.61 | Ki | 2.45 | Preclinical |
| CHEMBL472520 | 8.6 | Ki | 2.5 | Preclinical |
| CHEMBL488498 | 8.57 | Ki | 2.66 | Preclinical |
| CHEMBL488500 | 8.54 | Ki | 2.9 | Preclinical |
| CHEMBL96766 | 8.54 | Ki | 2.9 | Preclinical |
| CHEMBL453598 | 8.53 | Ki | 2.96 | Preclinical |
| CHEMBL230048 | 8.51 | Ki | 3.07 | Preclinical |
| CHEMBL488706 | 8.51 | Ki | 3.1 | Preclinical |
| CHEMBL461372 | 8.47 | Ki | 3.38 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 208 | 7.2 |
| cell-based format | 2 | 0 | — |
| assay format | 1 | 6 | 8.3 |
| subcellular format | 1 | 2 | 8.2 |