Cyclin-A2 · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P20248. Use UniProt P20248 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P20248 as the stable identity anchor, then attach disease evidence before program review.
Cyclin-A2
Review this target as Cyclin-A2, mapped to UniProt P20248. Sequence length is 432 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cyclin-A2 as ChEMBL target CHEMBL2582, mapped to UniProt P20248. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Cyclin-A2 is the right protein anchor across sources, using UniProt P20248 as the stable mapping.
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| Preferred Name | Cyclin-A2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P20248 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cyclin-A2 |
| UniProt Accession | P20248 |
| Component Type | Protein |
| Sequence Length | 432 aa |
Cyclin-A2
Review this target as Cyclin-A2, mapped to UniProt P20248. Sequence length is 432 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3393766 | 7.72 | Kd | 19.0 | Preclinical |
| CHEMBL488436 | 7.35 | IC50 | 45.0 | Preclinical |
| CHEMBL217362 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL5653589 | 6.3 | Kd | 505.12 | Preclinical |
| CHEMBL1241134 | 6.28 | IC50 | 530.0 | Preclinical |
| CHEMBL1241136 | 6.23 | IC50 | 590.0 | Preclinical |
| CHEMBL1241137 | 6.17 | IC50 | 680.0 | Preclinical |
| CHEMBL3752910 | 5.38 | Kd | 4217.1 | Preclinical |
| CHEMBL1241139 | 5.25 | IC50 | 5600.0 | Preclinical |
| CHEMBL1241138 | 4.92 | IC50 | 12000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 0 | — |
| single protein format | 4 | 11 | 6.1 |