5-hydroxytryptamine receptor 2B · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q02152. Use UniProt Q02152 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q02152 as the stable identity anchor, then attach disease evidence before program review.
5-hydroxytryptamine receptor 2B
Review this target as 5-hydroxytryptamine receptor 2B, mapped to UniProt Q02152. Sequence length is 479 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 5-hydroxytryptamine receptor 2B as ChEMBL target CHEMBL2583, mapped to UniProt Q02152. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether 5-hydroxytryptamine receptor 2B is the right protein anchor across sources, using UniProt Q02152 as the stable mapping.
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| Preferred Name | 5-hydroxytryptamine receptor 2B |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q02152 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 5-hydroxytryptamine receptor 2B |
| UniProt Accession | Q02152 |
| Component Type | Protein |
| Sequence Length | 479 aa |
5-hydroxytryptamine receptor 2B
Review this target as 5-hydroxytryptamine receptor 2B, mapped to UniProt Q02152. Sequence length is 479 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4114519 | 6.48 | Ki | 333.0 | Preclinical |
| CHEMBL3897835 | 6.36 | Ki | 441.0 | Preclinical |
| CHEMBL3946540 | 6.26 | Ki | 551.0 | Preclinical |
| CHEMBL4108986 | 6.22 | Ki | 600.0 | Preclinical |
| CHEMBL3986651 | 6.18 | Ki | 658.0 | Preclinical |
| CHEMBL4109218 | 6.11 | Ki | 770.0 | Preclinical |
| CHEMBL4111349 | 6.1 | Ki | 788.0 | Preclinical |
| CHEMBL3915107 | 5.96 | Ki | 1096.0 | Preclinical |
| CHEMBL4112090 | 5.88 | Ki | 1326.0 | Preclinical |
| CHEMBL3946661 | 5.84 | Ki | 1445.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 22 | 5.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |