Aminopeptidase N · SINGLE PROTEIN · Sus scrofa
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As of 2026-09-14Protein identity stays anchored to UniProt P15145. Use UniProt P15145 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P15145 as the stable identity anchor, then attach disease evidence before program review.
Aminopeptidase N
Review this target as Aminopeptidase N, mapped to UniProt P15145. Sequence length is 963 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Aminopeptidase N as ChEMBL target CHEMBL2590, mapped to UniProt P15145. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Aminopeptidase N is the right protein anchor across sources, using UniProt P15145 as the stable mapping.
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| Preferred Name | Aminopeptidase N |
| Target Type | SINGLE PROTEIN |
| Organism | Sus scrofa |
| UniProt | P15145 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Aminopeptidase N |
| UniProt Accession | P15145 |
| Component Type | Protein |
| Sequence Length | 963 aa |
Aminopeptidase N
Review this target as Aminopeptidase N, mapped to UniProt P15145. Sequence length is 963 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1821980 | 10.22 | Ki | 0.06 | Preclinical |
| CHEMBL1852660 | 10.22 | Ki | 0.06 | Preclinical |
| CHEMBL29292 | 9.3 | Ki | 0.5 | Clinical |
| CHEMBL4204736 | 9.22 | Ki | 0.6 | Preclinical |
| CHEMBL17107 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL289824 | 8.91 | Ki | 1.22 | Preclinical |
| CHEMBL1159920 | 8.82 | Ki | 1.5 | Preclinical |
| CHEMBL1235787 | 8.82 | Ki | 1.5 | Preclinical |
| CHEMBL3355110 | 8.82 | Ki | 1.5 | Preclinical |
| CHEMBL4216408 | 8.82 | Ki | 1.5 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 75 | 343 | 6.4 |
| assay format | 38 | 435 | 5.0 |
| microsome format | 10 | 120 | 5.6 |
| tissue-based format | 4 | 42 | 5.6 |
| subcellular format | 3 | 40 | 6.1 |