Use UniProt Q9Y0I0 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL2601 Target Snapshot
Adenosine transporter 1 · SINGLE PROTEIN · Trypanosoma brucei
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As of 2026-09-14Protein identity stays anchored to UniProt Q9Y0I0. Use UniProt Q9Y0I0 as the stable identity anchor, then attach disease evidence before program review.
Adenosine transporter 1
Review this target as Adenosine transporter 1, mapped to UniProt Q9Y0I0. Sequence length is 463 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Adenosine transporter 1 as ChEMBL target CHEMBL2601, mapped to UniProt Q9Y0I0. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Adenosine transporter 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Trypanosoma brucei |
| UniProt | Q9Y0I0 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Adenosine transporter 1 |
| UniProt Accession | Q9Y0I0 |
| Component Type | Protein |
| Sequence Length | 463 aa |
Adenosine transporter 1
How to read this target
Review this target as Adenosine transporter 1, mapped to UniProt Q9Y0I0. Sequence length is 463 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL542936 | 6.87 | Ki | 135.0 | Preclinical |
| CHEMBL29507 | 6.7 | Ki | 200.0 | Preclinical |
| CHEMBL544581 | 6.62 | Ki | 240.0 | Preclinical |
| CHEMBL542932 | 6.39 | Ki | 410.0 | Preclinical |
| CHEMBL553117 | 6.3 | Ki | 500.0 | Preclinical |
| CHEMBL27357 | 6.24 | Ki | 580.0 | Preclinical |
| CHEMBL545281 | 6.22 | Ki | 600.0 | Preclinical |
| CHEMBL287449 | 6.21 | Ki | 620.0 | Preclinical |
| CHEMBL542204 | 6.12 | Ki | 750.0 | Preclinical |
| CHEMBL541322 | 6.0 | Ki | 1000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 3 assays, 34 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 34 | 5.4 |