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Target Snapshot

CHEMBL2610 Target Snapshot

Calcium/calmodulin-dependent protein kinase type II subunit beta · SINGLE PROTEIN · Rattus norvegicus

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3Compounds
2Assays
0Approved Drugs
1.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-15

Protein identity stays anchored to UniProt P08413. Use UniProt P08413 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P08413 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-15
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Calcium/calmodulin-dependent protein kinase type II subunit beta as ChEMBL target CHEMBL2610, mapped to UniProt P08413. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Calcium/calmodulin-dependent protein kinase type II subunit beta
SINGLE PROTEIN · Rattus norvegicus
As of 2026-09-15
ChEMBL target ID
CHEMBL2610
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-15
www.ebi.ac.uk
UniProt accession
P08413
Calcium/calmodulin-dependent protein kinase type II subunit beta
UniProt accession via ChEMBL component mapping As of 2026-09-15
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-15
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Calcium/calmodulin-dependent protein kinase type II subunit beta is the right protein anchor across sources, using UniProt P08413 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameCalcium/calmodulin-dependent protein kinase type II subunit beta
Target TypeSINGLE PROTEIN
OrganismRattus norvegicus
UniProtP08413
ChEMBL ↗ UniProt ↗ NCBI Protein ↗

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelCalcium/calmodulin-dependent protein kinase type II subunit beta
UniProt AccessionP08413
Component TypeProtein
Sequence Length542 aa

Calcium/calmodulin-dependent protein kinase type II subunit beta

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Calcium/calmodulin-dependent protein kinase type II subunit beta, mapped to UniProt P08413. Sequence length is 542 aa.

Mapped IDP08413
Review nameCalcium/calmodulin-dependent protein kinase type II subunit beta
OrganismRattus norvegicus
Assay Mix

Activity Type Distribution

IC501.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL28324 6.0 IC50 1000.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
1
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

2
Total Assays
1
Tested Compounds
1
Assay Types
Binding — 2 assays, 1 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 1 0 —
tissue-based format 1 1 6.0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine