HLA class I histocompatibility antigen, A alpha chain · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P04439. Use UniProt P04439 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P04439 as the stable identity anchor, then attach disease evidence before program review.
HLA class I histocompatibility antigen, A alpha chain
Review this target as HLA class I histocompatibility antigen, A alpha chain, mapped to UniProt P04439. Sequence length is 365 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats HLA class I histocompatibility antigen, A alpha chain as ChEMBL target CHEMBL2632, mapped to UniProt P04439. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether HLA class I histocompatibility antigen, A alpha chain is the right protein anchor across sources, using UniProt P04439 as the stable mapping.
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| Preferred Name | HLA class I histocompatibility antigen, A alpha chain |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P04439 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | HLA class I histocompatibility antigen, A alpha chain |
| UniProt Accession | P04439 |
| Component Type | Protein |
| Sequence Length | 365 aa |
HLA class I histocompatibility antigen, A alpha chain
Review this target as HLA class I histocompatibility antigen, A alpha chain, mapped to UniProt P04439. Sequence length is 365 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL402482 | 8.77 | IC50 | 1.698 | Preclinical |
| CHEMBL412034 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL410648 | 8.66 | IC50 | 2.198 | Preclinical |
| CHEMBL415611 | 8.64 | IC50 | 2.301 | Preclinical |
| CHEMBL386178 | 8.49 | IC50 | 3.199 | Preclinical |
| CHEMBL386299 | 8.49 | IC50 | 3.199 | Preclinical |
| CHEMBL426344 | 8.48 | IC50 | 3.304 | Preclinical |
| CHEMBL402481 | 8.4 | IC50 | 3.999 | Preclinical |
| CHEMBL122183 | 8.37 | IC50 | 4.295 | Preclinical |
| CHEMBL110989 | 8.35 | IC50 | 4.498 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 159 | 7.0 |