Tyrosine-protein kinase CSK · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P41240. Use UniProt P41240 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P41240 as the stable identity anchor, then attach disease evidence before program review.
Tyrosine-protein kinase CSK
Review this target as Tyrosine-protein kinase CSK, mapped to UniProt P41240. Sequence length is 450 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Tyrosine-protein kinase CSK as ChEMBL target CHEMBL2634, mapped to UniProt P41240. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Tyrosine-protein kinase CSK |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P41240 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tyrosine-protein kinase CSK |
| UniProt Accession | P41240 |
| Component Type | Protein |
| Sequence Length | 450 aa |
Tyrosine-protein kinase CSK
Review this target as Tyrosine-protein kinase CSK, mapped to UniProt P41240. Sequence length is 450 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5416410 | 9.0 | Kd | 1.0 | Approved |
| CHEMBL5416410 | 8.89 | IC50 | 1.3 | Approved |
| CHEMBL591325 | 8.77 | IC50 | 1.7 | Preclinical |
| CHEMBL4582324 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL1873475 | 8.66 | IC50 | 2.2 | Approved |
| CHEMBL3647967 | 8.62 | IC50 | 2.4 | Preclinical |
| CHEMBL4443654 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL4445994 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL4537527 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL4545269 | 8.4 | IC50 | 4.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 409 | 111 | 6.5 |
| cell-based format | 44 | 7 | 5.7 |
| assay format | 40 | 2 | 7.1 |
| subcellular format | 35 | 14 | 6.4 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 26 | 5.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |
| single protein format | 1 | 0 | — |