Serine-threonine protein phosphatase 2A regulatory subunit · SINGLE PROTEIN · Gallus gallus
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt Q8AWE3. Use UniProt Q8AWE3 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8AWE3 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B
Review this target as Serine-threonine protein phosphatase 2A regulatory subunit, mapped to UniProt Q8AWE3. ChEMBL maps the protein component as Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B. Sequence length is 426 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine-threonine protein phosphatase 2A regulatory subunit as ChEMBL target CHEMBL2669, mapped to UniProt Q8AWE3. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Serine-threonine protein phosphatase 2A regulatory subunit is the right protein anchor across sources, using UniProt Q8AWE3 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Serine-threonine protein phosphatase 2A regulatory subunit |
| Target Type | SINGLE PROTEIN |
| Organism | Gallus gallus |
| UniProt | Q8AWE3 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B |
| UniProt Accession | Q8AWE3 |
| Component Type | Protein |
| Sequence Length | 426 aa |
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B
Review this target as Serine-threonine protein phosphatase 2A regulatory subunit, mapped to UniProt Q8AWE3. ChEMBL maps the protein component as Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B. Sequence length is 426 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL415297 | 10.52 | IC50 | 0.03 | Preclinical |
| CHEMBL444092 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL430266 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL4524071 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL17738 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL280487 | 9.35 | IC50 | 0.45 | Preclinical |
| CHEMBL505512 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL385212 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL15785 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL17060 | 8.47 | IC50 | 3.4 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 19 | 41 | 7.2 |
| tissue-based format | 1 | 6 | 6.1 |