Leucyl-cystinyl aminopeptidase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9UIQ6. Use UniProt Q9UIQ6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UIQ6 as the stable identity anchor, then attach disease evidence before program review.
Leucyl-cystinyl aminopeptidase
Review this target as Leucyl-cystinyl aminopeptidase, mapped to UniProt Q9UIQ6. Sequence length is 1025 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Leucyl-cystinyl aminopeptidase as ChEMBL target CHEMBL2693, mapped to UniProt Q9UIQ6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Leucyl-cystinyl aminopeptidase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UIQ6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Leucyl-cystinyl aminopeptidase |
| UniProt Accession | Q9UIQ6 |
| Component Type | Protein |
| Sequence Length | 1025 aa |
Leucyl-cystinyl aminopeptidase
Review this target as Leucyl-cystinyl aminopeptidase, mapped to UniProt Q9UIQ6. Sequence length is 1025 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5858644 | 9.05 | IC50 | 0.89 | Preclinical |
| CHEMBL6013513 | 9.03 | IC50 | 0.94 | Preclinical |
| CHEMBL6020816 | 9.02 | IC50 | 0.95 | Preclinical |
| CHEMBL5847848 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5900568 | 8.92 | IC50 | 1.2 | Preclinical |
| CHEMBL5845804 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL5925746 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL6046862 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL5832194 | 8.85 | IC50 | 1.4 | Preclinical |
| CHEMBL5875249 | 8.82 | IC50 | 1.5 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 19 | 193 | 6.0 |
| assay format | 4 | 241 | 8.1 |
| single protein format | 4 | 13 | 6.7 |