Serotonin 4 (5-HT4) receptor · SINGLE PROTEIN · Sus scrofa
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As of 2026-09-14Protein identity stays anchored to UniProt Q6Q253. Use UniProt Q6Q253 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q6Q253 as the stable identity anchor, then attach disease evidence before program review.
5-hydroxytryptamine receptor 4
Review this target as Serotonin 4 (5-HT4) receptor, mapped to UniProt Q6Q253. ChEMBL maps the protein component as 5-hydroxytryptamine receptor 4. Sequence length is 402 aa.
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This review treats Serotonin 4 (5-HT4) receptor as ChEMBL target CHEMBL2696, mapped to UniProt Q6Q253. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Serotonin 4 (5-HT4) receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Sus scrofa |
| UniProt | Q6Q253 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 5-hydroxytryptamine receptor 4 |
| UniProt Accession | Q6Q253 |
| Component Type | Protein |
| Sequence Length | 402 aa |
5-hydroxytryptamine receptor 4
Review this target as Serotonin 4 (5-HT4) receptor, mapped to UniProt Q6Q253. ChEMBL maps the protein component as 5-hydroxytryptamine receptor 4. Sequence length is 402 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL358119 | 10.2 | Ki | 0.0631 | Preclinical |
| CHEMBL114112 | 10.1 | Kd | 0.08 | Preclinical |
| CHEMBL145075 | 10.1 | Ki | 0.07943 | Preclinical |
| CHEMBL3126112 | 10.1 | Kd | 0.08 | Preclinical |
| CHEMBL68131 | 9.9 | Ki | 0.1259 | Preclinical |
| CHEMBL143862 | 9.7 | Ki | 0.1995 | Preclinical |
| CHEMBL143426 | 8.6 | Ki | 2.512 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 2 | 5 | 9.7 |
| cell membrane format | 1 | 2 | 10.1 |
| single protein format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 2 | 0 | — |