Pancreatic alpha-amylase · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P00689. Use UniProt P00689 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P00689 as the stable identity anchor, then attach disease evidence before program review.
Pancreatic alpha-amylase
Review this target as Pancreatic alpha-amylase, mapped to UniProt P00689. Sequence length is 508 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Pancreatic alpha-amylase as ChEMBL target CHEMBL2699, mapped to UniProt P00689. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Pancreatic alpha-amylase is the right protein anchor across sources, using UniProt P00689 as the stable mapping.
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| Preferred Name | Pancreatic alpha-amylase |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P00689 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Pancreatic alpha-amylase |
| UniProt Accession | P00689 |
| Component Type | Protein |
| Sequence Length | 508 aa |
Pancreatic alpha-amylase
Review this target as Pancreatic alpha-amylase, mapped to UniProt P00689. Sequence length is 508 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL286008 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL284137 | 7.68 | IC50 | 21.0 | Preclinical |
| CHEMBL26505 | 7.34 | IC50 | 46.0 | Clinical |
| CHEMBL443780 | 7.28 | IC50 | 52.0 | Preclinical |
| CHEMBL285440 | 6.72 | IC50 | 190.0 | Preclinical |
| CHEMBL285898 | 6.42 | IC50 | 380.0 | Preclinical |
| CHEMBL24369 | 5.57 | IC50 | 2700.0 | Preclinical |
| CHEMBL196 | 4.58 | IC50 | 26500.0 | Approved |
| CHEMBL39670 | 4.55 | IC50 | 28000.0 | Preclinical |
| CHEMBL196 | 4.36 | Ki | 43400.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 3 | 4.4 |
| assay format | 1 | 7 | 7.0 |