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Target Snapshot

CHEMBL2703 Target Snapshot

D(2) dopamine receptor · SINGLE PROTEIN · Canis lupus familiaris

71Compounds
5Assays
0Approved Drugs
1.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt Q9GJU1. Use UniProt Q9GJU1 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9GJU1 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats D(2) dopamine receptor as ChEMBL target CHEMBL2703, mapped to UniProt Q9GJU1. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
D(2) dopamine receptor
SINGLE PROTEIN · Canis lupus familiaris
As of 2026-09-13
ChEMBL target ID
CHEMBL2703
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
Q9GJU1
D(2) dopamine receptor
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether D(2) dopamine receptor is the right protein anchor across sources, using UniProt Q9GJU1 as the stable mapping.

Jump to Protein Context
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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelD(2) dopamine receptor
UniProt AccessionQ9GJU1
Component TypeProtein
Sequence Length443 aa

D(2) dopamine receptor

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as D(2) dopamine receptor, mapped to UniProt Q9GJU1. Sequence length is 443 aa.

Mapped IDQ9GJU1
Review nameD(2) dopamine receptor
OrganismCanis lupus familiaris
Clinical Profile

Clinical Phase Distribution

1
Phase III
Assay Mix

Activity Type Distribution

IC501.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL26 6.7 IC50 200.0 Clinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
1
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

5
Total Assays
1
Tested Compounds
2
Assay Types
Functional — 3 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 3 0
Binding — 2 assays, 1 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 2 1 6.7

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine