Pepsin A · SINGLE PROTEIN · Sus scrofa
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P00791. Use UniProt P00791 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P00791 as the stable identity anchor, then attach disease evidence before program review.
Pepsin A
Review this target as Pepsin A, mapped to UniProt P00791. Sequence length is 385 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Pepsin A as ChEMBL target CHEMBL2714, mapped to UniProt P00791. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Pepsin A is the right protein anchor across sources, using UniProt P00791 as the stable mapping.
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| Preferred Name | Pepsin A |
| Target Type | SINGLE PROTEIN |
| Organism | Sus scrofa |
| UniProt | P00791 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Pepsin A |
| UniProt Accession | P00791 |
| Component Type | Protein |
| Sequence Length | 385 aa |
Pepsin A
Review this target as Pepsin A, mapped to UniProt P00791. Sequence length is 385 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL74043 | 10.75 | Ki | 0.0177 | Preclinical |
| CHEMBL73985 | 10.4 | Ki | 0.0394 | Preclinical |
| CHEMBL169533 | 10.34 | Ki | 0.046 | Preclinical |
| CHEMBL322823 | 10.34 | Ki | 0.0457 | Preclinical |
| CHEMBL296588 | 10.25 | Ki | 0.056 | Clinical |
| CHEMBL165448 | 9.74 | Ki | 0.18 | Preclinical |
| CHEMBL262137 | 9.51 | Ki | 0.31 | Preclinical |
| CHEMBL75248 | 9.46 | Ki | 0.346 | Preclinical |
| CHEMBL3142505 | 9.19 | Ki | 0.64 | Preclinical |
| CHEMBL325506 | 9.05 | Ki | 0.9 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 92 | 136 | 7.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 11 | 6.0 |