Histone deacetylase 7 · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt Q8WUI4. Use UniProt Q8WUI4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8WUI4 as the stable identity anchor, then attach disease evidence before program review.
Histone deacetylase 7
Review this target as Histone deacetylase 7, mapped to UniProt Q8WUI4. Sequence length is 952 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Histone deacetylase 7 as ChEMBL target CHEMBL2716, mapped to UniProt Q8WUI4. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Histone deacetylase 7 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8WUI4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Histone deacetylase 7 |
| UniProt Accession | Q8WUI4 |
| Component Type | Protein |
| Sequence Length | 952 aa |
Histone deacetylase 7
Review this target as Histone deacetylase 7, mapped to UniProt Q8WUI4. Sequence length is 952 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3692689 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL2105763 | 8.77 | Ki | 1.7 | Clinical |
| CHEMBL98 | 8.7 | IC50 | 2.0 | Approved |
| CHEMBL483254 | 8.64 | Ki | 2.3 | Approved |
| CHEMBL484073 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL2105763 | 8.39 | IC50 | 4.04 | Clinical |
| CHEMBL490018 | 8.36 | IC50 | 4.4 | Preclinical |
| CHEMBL113537 | 8.33 | Ki | 4.7 | Preclinical |
| CHEMBL356066 | 8.21 | IC50 | 6.11 | Clinical |
| CHEMBL484489 | 8.2 | IC50 | 6.3 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 233 | 289 | 5.9 |
| cell-based format | 66 | 80 | 5.8 |
| assay format | 39 | 47 | 5.3 |
| subcellular format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 5 | 6.4 |
| single protein format | 3 | 1 | 5.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 1 | 5.0 |