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Target Snapshot

CHEMBL2720 Target Snapshot

Gastrin/cholecystokinin type B receptor · SINGLE PROTEIN · Bos taurus

35Compounds
4Assays
0Approved Drugs
35.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P79266. Use UniProt P79266 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P79266 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Gastrin/cholecystokinin type B receptor as ChEMBL target CHEMBL2720, mapped to UniProt P79266. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Gastrin/cholecystokinin type B receptor
SINGLE PROTEIN · Bos taurus
As of 2026-09-14
ChEMBL target ID
CHEMBL2720
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P79266
Gastrin/cholecystokinin type B receptor
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Gastrin/cholecystokinin type B receptor is the right protein anchor across sources, using UniProt P79266 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelGastrin/cholecystokinin type B receptor
UniProt AccessionP79266
Component TypeProtein
Sequence Length454 aa

Gastrin/cholecystokinin type B receptor

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Gastrin/cholecystokinin type B receptor, mapped to UniProt P79266. Sequence length is 454 aa.

Mapped IDP79266
Review nameGastrin/cholecystokinin type B receptor
OrganismBos taurus
Assay Mix

Activity Type Distribution

IC5035.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL122438 10.54 IC50 0.029 Preclinical
CHEMBL126008 10.07 IC50 0.085 Preclinical
CHEMBL331408 9.32 IC50 0.48 Preclinical
CHEMBL2079606 9.3 IC50 0.5 Preclinical
CHEMBL386376 9.04 IC50 0.91 Preclinical
CHEMBL433647 8.74 IC50 1.8 Preclinical
CHEMBL430906 8.51 IC50 3.1 Preclinical
CHEMBL2112635 8.47 IC50 3.4 Preclinical
CHEMBL2370122 8.36 IC50 4.4 Preclinical
CHEMBL267849 8.36 IC50 4.4 Preclinical
Distribution

pChEMBL Value Distribution

3
5.0
2
5.5
1
6.0
4
6.5
7
7.0
4
7.5
7
8.0
2
8.5
3
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

4
Total Assays
35
Tested Compounds
1
Assay Types
Binding — 4 assays, 35 compounds
BAO Format Assays Compounds Avg pChEMBL
tissue-based format 3 19 7.7
cell membrane format 1 16 7.5

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine