Sialidase-1 · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q99519. Use UniProt Q99519 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q99519 as the stable identity anchor, then attach disease evidence before program review.
Sialidase-1
Review this target as Sialidase-1, mapped to UniProt Q99519. Sequence length is 415 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sialidase-1 as ChEMBL target CHEMBL2726, mapped to UniProt Q99519. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Sialidase-1 is the right protein anchor across sources, using UniProt Q99519 as the stable mapping.
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| Preferred Name | Sialidase-1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q99519 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sialidase-1 |
| UniProt Accession | Q99519 |
| Component Type | Protein |
| Sequence Length | 415 aa |
Sialidase-1
Review this target as Sialidase-1, mapped to UniProt Q99519. Sequence length is 415 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4278858 | 7.28 | Ki | 53.0 | Preclinical |
| CHEMBL4290253 | 6.85 | IC50 | 140.0 | Preclinical |
| CHEMBL4291908 | 6.75 | Ki | 180.0 | Preclinical |
| CHEMBL4281290 | 6.62 | Ki | 240.0 | Preclinical |
| CHEMBL4279593 | 6.46 | IC50 | 350.0 | Preclinical |
| CHEMBL4283057 | 6.4 | IC50 | 400.0 | Preclinical |
| CHEMBL4291908 | 6.38 | IC50 | 420.0 | Preclinical |
| CHEMBL4453020 | 6.38 | IC50 | 420.0 | Preclinical |
| CHEMBL4472555 | 6.26 | IC50 | 550.0 | Preclinical |
| CHEMBL4566262 | 6.24 | IC50 | 580.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 22 | 69 | 5.2 |
| single protein format | 5 | 8 | 4.3 |