Beta-glucuronidase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P08236. Use UniProt P08236 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P08236 as the stable identity anchor, then attach disease evidence before program review.
Beta-glucuronidase
Review this target as Beta-glucuronidase, mapped to UniProt P08236. Sequence length is 651 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-glucuronidase as ChEMBL target CHEMBL2728, mapped to UniProt P08236. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Beta-glucuronidase is the right protein anchor across sources, using UniProt P08236 as the stable mapping.
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| Preferred Name | Beta-glucuronidase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P08236 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-glucuronidase |
| UniProt Accession | P08236 |
| Component Type | Protein |
| Sequence Length | 651 aa |
Beta-glucuronidase
Review this target as Beta-glucuronidase, mapped to UniProt P08236. Sequence length is 651 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3980115 | 9.01 | IC50 | 0.984 | Preclinical |
| CHEMBL3980115 | 8.47 | EC50 | 3.41 | Preclinical |
| CHEMBL5409470 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL5273557 | 8.01 | IC50 | 9.75 | Preclinical |
| CHEMBL3903683 | 7.75 | EC50 | 17.7 | Preclinical |
| CHEMBL4635113 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL1236932 | 7.55 | EC50 | 28.3 | Preclinical |
| CHEMBL4635884 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL4633508 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL4647420 | 7.4 | IC50 | 40.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 36 | 366 | 5.4 |
| cell-based format | 2 | 9 | 6.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 0 | — |
| assay format | 1 | 0 | — |