Gamma-aminobutyric acid type B receptor subunit 1 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q9Z0U4. Use UniProt Q9Z0U4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9Z0U4 as the stable identity anchor, then attach disease evidence before program review.
Gamma-aminobutyric acid type B receptor subunit 1
Review this target as Gamma-aminobutyric acid type B receptor subunit 1, mapped to UniProt Q9Z0U4. Sequence length is 960 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Gamma-aminobutyric acid type B receptor subunit 1 as ChEMBL target CHEMBL2753, mapped to UniProt Q9Z0U4. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Gamma-aminobutyric acid type B receptor subunit 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q9Z0U4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Gamma-aminobutyric acid type B receptor subunit 1 |
| UniProt Accession | Q9Z0U4 |
| Component Type | Protein |
| Sequence Length | 960 aa |
Gamma-aminobutyric acid type B receptor subunit 1
Review this target as Gamma-aminobutyric acid type B receptor subunit 1, mapped to UniProt Q9Z0U4. Sequence length is 960 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL112203 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL3640618 | 8.01 | IC50 | 9.79 | Preclinical |
| CHEMBL38856 | 7.9 | IC50 | 12.6 | Preclinical |
| CHEMBL3640615 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL112710 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL3640616 | 7.75 | IC50 | 17.9 | Preclinical |
| CHEMBL5742935 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL5743455 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL5748498 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL5750273 | 7.52 | IC50 | 30.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 87 | 6.2 |
| single protein format | 2 | 180 | 7.2 |
| subcellular format | 1 | 0 | — |