Use UniProt P56560 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL2756 Target Snapshot
Amine oxidase [flavin-containing] B · SINGLE PROTEIN · Bos taurus
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As of 2026-09-14Protein identity stays anchored to UniProt P56560. Use UniProt P56560 as the stable identity anchor, then attach disease evidence before program review.
Amine oxidase [flavin-containing] B
Review this target as Amine oxidase [flavin-containing] B, mapped to UniProt P56560. Sequence length is 520 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Amine oxidase [flavin-containing] B as ChEMBL target CHEMBL2756, mapped to UniProt P56560. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Amine oxidase [flavin-containing] B is the right protein anchor across sources, using UniProt P56560 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Amine oxidase [flavin-containing] B |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P56560 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Amine oxidase [flavin-containing] B |
| UniProt Accession | P56560 |
| Component Type | Protein |
| Sequence Length | 520 aa |
Amine oxidase [flavin-containing] B
How to read this target
Review this target as Amine oxidase [flavin-containing] B, mapped to UniProt P56560. Sequence length is 520 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL385117 | 9.09 | Ki | 0.8128 | Preclinical |
| CHEMBL224562 | 9.0 | Ki | 1.0 | Preclinical |
| CHEMBL424940 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL220548 | 8.88 | Ki | 1.318 | Preclinical |
| CHEMBL459336 | 8.82 | Ki | 1.5 | Preclinical |
| CHEMBL2096866 | 8.57 | Ki | 2.7 | Preclinical |
| CHEMBL375007 | 8.39 | Ki | 4.074 | Preclinical |
| CHEMBL218059 | 8.22 | IC50 | 6.026 | Preclinical |
| CHEMBL387736 | 8.22 | Ki | 6.0 | Preclinical |
| CHEMBL385124 | 8.15 | Ki | 7.079 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 94 assays, 371 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 50 | 70 | 5.0 |
| assay format | 31 | 151 | 5.9 |
| mitochondrion format | 12 | 149 | 6.2 |
| tissue-based format | 1 | 1 | 7.7 |