Ectonucleoside triphosphate diphosphohydrolase 1 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P97687. Use UniProt P97687 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P97687 as the stable identity anchor, then attach disease evidence before program review.
Ectonucleoside triphosphate diphosphohydrolase 1
Review this target as Ectonucleoside triphosphate diphosphohydrolase 1, mapped to UniProt P97687. Sequence length is 511 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Ectonucleoside triphosphate diphosphohydrolase 1 as ChEMBL target CHEMBL2767, mapped to UniProt P97687. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Ectonucleoside triphosphate diphosphohydrolase 1 is the right protein anchor across sources, using UniProt P97687 as the stable mapping.
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| Preferred Name | Ectonucleoside triphosphate diphosphohydrolase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P97687 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ectonucleoside triphosphate diphosphohydrolase 1 |
| UniProt Accession | P97687 |
| Component Type | Protein |
| Sequence Length | 511 aa |
Ectonucleoside triphosphate diphosphohydrolase 1
Review this target as Ectonucleoside triphosphate diphosphohydrolase 1, mapped to UniProt P97687. Sequence length is 511 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL597197 | 6.48 | Ki | 328.0 | Preclinical |
| CHEMBL4285649 | 5.98 | IC50 | 1050.0 | Preclinical |
| CHEMBL4293491 | 5.96 | IC50 | 1100.0 | Preclinical |
| CHEMBL4295005 | 5.64 | IC50 | 2300.0 | Preclinical |
| CHEMBL4290501 | 5.21 | IC50 | 6210.0 | Preclinical |
| CHEMBL4291645 | 5.04 | IC50 | 9020.0 | Preclinical |
| CHEMBL4279910 | 5.0 | IC50 | 10100.0 | Preclinical |
| CHEMBL271673 | 4.8 | Ki | 15700.0 | Preclinical |
| CHEMBL223344 | 4.7 | Ki | 20000.0 | Preclinical |
| CHEMBL4744335 | 4.7 | Ki | 20000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 5 | 4.5 |
| cell-based format | 3 | 26 | 4.8 |