Retinoic acid receptor alpha · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P11416. Use UniProt P11416 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P11416 as the stable identity anchor, then attach disease evidence before program review.
Retinoic acid receptor alpha
Review this target as Retinoic acid receptor alpha, mapped to UniProt P11416. Sequence length is 462 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Retinoic acid receptor alpha as ChEMBL target CHEMBL2792, mapped to UniProt P11416. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Retinoic acid receptor alpha is the right protein anchor across sources, using UniProt P11416 as the stable mapping.
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| Preferred Name | Retinoic acid receptor alpha |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P11416 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Retinoic acid receptor alpha |
| UniProt Accession | P11416 |
| Component Type | Protein |
| Sequence Length | 462 aa |
Retinoic acid receptor alpha
Review this target as Retinoic acid receptor alpha, mapped to UniProt P11416. Sequence length is 462 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL38 | 8.92 | EC50 | 1.2 | Approved |
| CHEMBL4572914 | 8.4 | EC50 | 4.0 | Preclinical |
| CHEMBL38 | 8.3 | IC50 | 5.0 | Approved |
| CHEMBL705 | 8.15 | Kd | 7.0 | Approved |
| CHEMBL333032 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL345298 | 8.04 | EC50 | 9.2 | Preclinical |
| CHEMBL46398 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL38 | 7.82 | Kd | 15.0 | Approved |
| CHEMBL4449668 | 7.8 | EC50 | 16.0 | Preclinical |
| CHEMBL44478 | 7.75 | EC50 | 18.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 10 | 24 | 7.5 |
| single protein format | 9 | 17 | 7.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 0 | — |
| cell-based format | 1 | 0 | — |