Substance-K receptor · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P30549. Use UniProt P30549 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P30549 as the stable identity anchor, then attach disease evidence before program review.
Substance-K receptor
Review this target as Substance-K receptor, mapped to UniProt P30549. Sequence length is 384 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Substance-K receptor as ChEMBL target CHEMBL2813, mapped to UniProt P30549. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Substance-K receptor is the right protein anchor across sources, using UniProt P30549 as the stable mapping.
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| Preferred Name | Substance-K receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P30549 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Substance-K receptor |
| UniProt Accession | P30549 |
| Component Type | Protein |
| Sequence Length | 384 aa |
Substance-K receptor
Review this target as Substance-K receptor, mapped to UniProt P30549. Sequence length is 384 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL540553 | 8.69 | IC50 | 2.05 | Preclinical |
| CHEMBL553617 | 8.66 | IC50 | 2.19 | Preclinical |
| CHEMBL315814 | 8.5 | IC50 | 3.13 | Preclinical |
| CHEMBL313931 | 8.44 | IC50 | 3.64 | Preclinical |
| CHEMBL553451 | 8.35 | IC50 | 4.51 | Preclinical |
| CHEMBL554092 | 8.11 | IC50 | 7.77 | Preclinical |
| CHEMBL539021 | 8.08 | IC50 | 8.4 | Preclinical |
| CHEMBL84055 | 8.03 | IC50 | 9.39 | Preclinical |
| CHEMBL553554 | 7.99 | IC50 | 10.2 | Preclinical |
| CHEMBL432183 | 7.93 | IC50 | 11.8 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 20 | 7.8 |