Use UniProt P48730 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL2828 Target Snapshot
Casein kinase I isoform delta · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P48730. Use UniProt P48730 as the stable identity anchor, then attach disease evidence before program review.
Casein kinase I isoform delta
Review this target as Casein kinase I isoform delta, mapped to UniProt P48730. Sequence length is 415 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Casein kinase I isoform delta as ChEMBL target CHEMBL2828, mapped to UniProt P48730. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Casein kinase I isoform delta is the right protein anchor across sources, using UniProt P48730 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Casein kinase I isoform delta |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P48730 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Casein kinase I isoform delta |
| UniProt Accession | P48730 |
| Component Type | Protein |
| Sequence Length | 415 aa |
Casein kinase I isoform delta
How to read this target
Review this target as Casein kinase I isoform delta, mapped to UniProt P48730. Sequence length is 415 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5809866 | 10.47 | IC50 | 0.034 | Preclinical |
| CHEMBL5914602 | 10.47 | IC50 | 0.034 | Preclinical |
| CHEMBL5819750 | 10.22 | IC50 | 0.06 | Preclinical |
| CHEMBL5854794 | 10.19 | IC50 | 0.064 | Preclinical |
| CHEMBL5865470 | 10.07 | IC50 | 0.085 | Preclinical |
| CHEMBL5757040 | 10.04 | IC50 | 0.091 | Preclinical |
| CHEMBL5927613 | 10.02 | IC50 | 0.096 | Preclinical |
| CHEMBL3961316 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL3962177 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL5743590 | 10.0 | IC50 | 0.1 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 513 assays, 1,172 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 382 | 1,058 | 7.9 |
| assay format | 82 | 10 | 5.5 |
| cell-based format | 33 | 88 | 6.8 |
| subcellular format | 16 | 16 | 5.8 |
Functional — 4 assays, 316 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 316 | 6.2 |
ADME — 1 assays, 0 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |