Peroxisome proliferator-activated receptor alpha · SINGLE PROTEIN · Canis lupus familiaris
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As of 2026-09-14Protein identity stays anchored to UniProt Q95N78. Use UniProt Q95N78 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q95N78 as the stable identity anchor, then attach disease evidence before program review.
Peroxisome proliferator-activated receptor alpha
Review this target as Peroxisome proliferator-activated receptor alpha, mapped to UniProt Q95N78. Sequence length is 468 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Peroxisome proliferator-activated receptor alpha as ChEMBL target CHEMBL2847, mapped to UniProt Q95N78. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Peroxisome proliferator-activated receptor alpha |
| Target Type | SINGLE PROTEIN |
| Organism | Canis lupus familiaris |
| UniProt | Q95N78 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Peroxisome proliferator-activated receptor alpha |
| UniProt Accession | Q95N78 |
| Component Type | Protein |
| Sequence Length | 468 aa |
Peroxisome proliferator-activated receptor alpha
Review this target as Peroxisome proliferator-activated receptor alpha, mapped to UniProt Q95N78. Sequence length is 468 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL552240 | 9.26 | EC50 | 0.55 | Preclinical |
| CHEMBL190334 | 8.7 | EC50 | 2.0 | Preclinical |
| CHEMBL190603 | 8.7 | EC50 | 2.0 | Preclinical |
| CHEMBL190976 | 8.7 | EC50 | 2.0 | Preclinical |
| CHEMBL363780 | 8.7 | EC50 | 2.0 | Preclinical |
| CHEMBL192638 | 8.1 | EC50 | 8.0 | Preclinical |
| CHEMBL363006 | 8.0 | EC50 | 10.0 | Preclinical |
| CHEMBL190968 | 7.7 | EC50 | 20.0 | Preclinical |
| CHEMBL192609 | 7.58 | EC50 | 26.0 | Preclinical |
| CHEMBL192582 | 7.38 | EC50 | 42.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 7 | 16 | 7.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 1 | 7.0 |