Methylated-DNA--protein-cysteine methyltransferase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P16455. Use UniProt P16455 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P16455 as the stable identity anchor, then attach disease evidence before program review.
Methylated-DNA--protein-cysteine methyltransferase
Review this target as Methylated-DNA--protein-cysteine methyltransferase, mapped to UniProt P16455. Sequence length is 207 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Methylated-DNA--protein-cysteine methyltransferase as ChEMBL target CHEMBL2864, mapped to UniProt P16455. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Methylated-DNA--protein-cysteine methyltransferase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P16455 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Methylated-DNA--protein-cysteine methyltransferase |
| UniProt Accession | P16455 |
| Component Type | Protein |
| Sequence Length | 207 aa |
Methylated-DNA--protein-cysteine methyltransferase
Review this target as Methylated-DNA--protein-cysteine methyltransferase, mapped to UniProt P16455. Sequence length is 207 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL337677 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL339133 | 8.52 | IC50 | 3.0 | Clinical |
| CHEMBL146769 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL485756 | 8.05 | IC50 | 9.0 | Preclinical |
| CHEMBL151579 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL4454794 | 7.62 | Ki | 24.0 | Preclinical |
| CHEMBL2171205 | 7.6 | IC50 | 25.0 | Preclinical |
| CHEMBL129850 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL131510 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL336947 | 7.5 | IC50 | 32.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 58 | 47 | 6.2 |
| single protein format | 19 | 36 | 6.3 |
| assay format | 6 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |
| single protein format | 1 | 0 | — |